Maze Therapeutics, Inc.(MAZE)
NASDAQ
$31.01
-0.94 (-2.94%)

Maze Therapeutics, Inc.(MAZE)Company Profile & Business
NASDAQ

Company Profile

Business overview, scale, and footprint

Company NameMaze Therapeutics, Inc.
Ticker SymbolMAZE
ExchangeNGM
SectorHealthcare
IndustryBiotechnology
Employees141
CEODr. Jason V. Coloma M.B.A., M.P.H., Ph.D.
Founded2017
HeadquartersSouth San Francisco, CA, United States
CountryUnited States
Websitemazetx.com
Next Earnings DateNov 5, 2026

Business Overview

Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor that is in phase II ready clinical trial for the treatment of phenylketonuria and chronic kidney disease. The company also develops MZE001, an investigational oral small molecule inhibitor of muscle-specific glycogen synthase clinical program for the treatment of Pompe disease. It has a license agreement with Trace Neuroscience, Inc. to discovery research program targets UNC13A; the Shionogi & Co., Ltd to research, develop, manufacture, and commercialize MZE001; and Neurocrine Biosciences, Inc. to discover research program that targets ATXN2.

The company was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.

Insider Transactions

Open-market activity and option exercises

Insider Activity Summary

Insider trading activity for Maze Therapeutics, Inc. (MAZE) between May 22, 2026 and Oct 1, 2026 consists of 49 total transactions. Among these, company executives and board members conducted 0 buys (totaling 0 shares) and 49 sells (totaling 373,520 shares). This activity resulted in a net change of -373,520 shares, reflecting net selling pressure with an estimated net sales value of $10.08M.

49 insider transactions found. Showing 10 of 49 transactions.

Show:entries
Insider NameRelation to CompanyShares ChangedPriceTransaction Date
Bernstein HaroldPresident, R&D & CMO-16,141$26.93Oct 1, 2026
Coloma Jason VChief Executive Officer-2,593$27.02Oct 1, 2026
Coloma Jason VChief Executive Officer-31,908$27.02Oct 1, 2026
Dandekar AtulCSBO-7,500$27.06Sep 29, 2026
Bernstein HaroldPresident, R&D & CMO-9,705$26.22Sep 4, 2026
Coloma Jason VChief Executive Officer-11,282$26.01Sep 3, 2026
Bernstein HaroldPresident, R&D & CMO-5,130$26.01Sep 3, 2026
Courtney PhillipsGC and Corp. Secretary-1,990$26.01Sep 3, 2026
Courtney PhillipsGC and Corp. Secretary-22$25.78Sep 3, 2026
Dandekar AtulCSBO-3,207$26.01Sep 3, 2026
Page 1 of 5 (49 total transactions)