Karyopharm Therapeutics Inc.(KPTI)Earnings Date, History & Expected Move

Next report date, beat rate and options-implied move

Next report

Oct 29, 2026

KPTI is scheduled to report on Oct 29, 2026, usually before the market opens. Analysts expect EPS of -$0.96.

Next report

Oct 29, 2026

In 5 days · usually before open

EPS beat rate

50%

6 of 12 quarters

Avg move after earnings

±9.0%

Up 20% of the time · last 10

Options-implied move

—

No reliable options quote yet

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EPS: Actual vs Estimate

Reported EPS against the consensus estimate, last 12 quarters.

Green beat or met, red missed, amber sources differ.

Stock Reaction After Earnings

Close-to-close move in the first session that reflected each report.

Dashed lines mark the average actual move (±9.0%).

Did the stock rise after good news?

The next-day move after each of its last 5 EPS beats and 5 misses.

When it beat expectations

5 reports

▼ Fell 5×

When it missed expectations

5 reports

▲ Rose 2×

▼ Fell 3×

In plain words: it beat expectations 5 times, but the stock still fell 5 of those 5 times.

Report by report

Aug '26
Missed
▼ -2.0%
Feb '26
Missed
▲ +21.3%
Nov '25
Missed
▲ +4.7%
Aug '25
Missed
▼ -4.3%
May '25
Beat
▼ -20.0%
Feb '25
Beat
▼ -4.8%
Nov '24
Beat
▼ -9.3%
Aug '24
Beat
▼ -3.6%
May '24
Beat
▼ -7.3%
Feb '24
Missed
▼ -12.8%

Clear beats and misses with a known reaction only. What counts as a beat

After an EPS beat

-9.0%

average next-day move · up 0% of 5 times

After an EPS miss

+1.4%

average next-day move · up 40% of 5 times

Why did KPTI fall after beating earnings?

7 of KPTI's last 10 reactions went against the EPS result. What stands out in each:

KPTI beat EPS estimates in 5 quarters, and the stock still closed lower the next day 5 times. In 4 of the 5 where we have price data, the stock had already run up before the report.

May 12, 2025EPS beat +10.4%stock -20.0% next day
- It had risen 43.4% in the 20 trading sessions before the report, so good news may already have been priced in.
- It opened 6.5% lower as soon as trading resumed.
Feb 19, 2025EPS beat +10.7%stock -4.8% next day
- It opened 2.1% lower as soon as trading resumed.
Nov 5, 2024EPS beat +0.5%stock -9.3% next day
- It had risen 7.2% in the 20 trading sessions before the report, so good news may already have been priced in.
- The EPS beat was small (+0.5%).
- It opened 2.5% lower as soon as trading resumed.
Aug 6, 2024EPS beat +2.9%stock -3.6% next day
- It had risen 10.3% in the 20 trading sessions before the report, so good news may already have been priced in.
- It opened 6.8% higher, but sellers took over and it closed -3.6%.
May 8, 2024EPS beat +2.8%stock -7.3% next day
- It had risen 6.8% in the final week before the report, so good news may already have been priced in.
- It opened 2.7% higher, but sellers took over and it closed -7.3%.

Rose despite an EPS miss (2 of 5)

Feb 12, 2026EPS missed -11.5%stock +21.3% next day
- It had already fallen 6.8% in the 20 trading sessions before the report, so weak results may have been expected.
Nov 3, 2025EPS missed -17.5%stock +4.7% next day
- It had already fallen 9.1% in the 20 trading sessions before the report, so weak results may have been expected.

Patterns in estimates and prices, not confirmed causes: how we read them.

Was KPTI's earnings move already priced in?

KPTI's move in the month before each of its last 10 reports, against what it did after.

Avg move in the month before

-1.7%

last 10 reports

Higher before the report

40%

of the time

After a run-up of 3%+

Fell 100%

4 reports, avg -11.4%

After a drop of 3%+

Rose 33%

6 reports, avg +1.3%

How the run-up is measured (a move of 5% or more counts as large).

Before vs after each report

Grey: the month before each of the last 10 reports. Green or red: the day after.

Past reports only. How the run-up is measured

Does KPTI hold its opening gap after earnings?

KPTI's opening move after each report and where it closed that day.

In 7 reports KPTI opened at least 1% away from the previous close. It gave back half or more of that gap by the close 4 of 7 times (57%), and fully reversed 4 times. Gaps up faded 3 of 3; gaps down recovered 1 of 4.

Feb 12, 2026Reversed
Opened -8.8%, closed +21.3%
Aug 11, 2025Reversed
Opened +1.5%, closed -4.3%
May 12, 2025Held
Opened -6.5%, closed -20.0%
Feb 19, 2025Held
Opened -2.1%, closed -4.8%
Nov 5, 2024Held
Opened -2.5%, closed -9.3%
Aug 6, 2024Reversed
Opened +6.8%, closed -3.6%
May 8, 2024Reversed
Opened +2.7%, closed -7.3%

How gaps, fades and reversals are defined

What the history says

It fell after 5 of its 5 EPS beats (100%): beating estimates has not been enough on its own.

KPTI earnings history

Last 12 reported quarters with the stock's reaction.

Swipe sideways to see every column →

Report date	Time	EPS est.	EPS actual	Surprise	1-day move	3-day move
Aug 13, 2026	Before open	-$1.39	-$2.32	-66.9%	-1.97%	-10.84%
May 14, 2026	Before open	-$1.44	-$1.24	+13.9%	—	—
Feb 12, 2026	Before open	-$2.00	-$2.23	-11.5%	+21.30%	+27.54%
Nov 3, 2025	Before open	-$3.25	-$3.82	-17.5%	+4.66%	-7.59%
Aug 11, 2025	Before open	-$3.91	-$4.07	-4.1%	-4.31%	+12.94%
May 12, 2025	After close	-$3.09	-$2.77	+10.4%	-20.00%	-11.54%
Feb 19, 2025	Before open	-$4.03	-$3.60	+10.7%	-4.76%	-5.08%
Nov 5, 2024	Before open	-$3.92	-$3.90	+0.5%	-9.32%	-5.47%
Aug 6, 2024	Before open	-$4.47	-$4.34	+2.9%	-3.56%	-3.79%
May 8, 2024	Before open	-$4.94	-$4.80	+2.8%	-7.27%	-0.91%
Feb 29, 2024	Before open	-$4.65	-$5.40	-16.1%	-12.78%	-1.50%
Nov 2, 2023	Before open	-$4.29	-$4.50	-4.9%	—	—

Consensus for the next report: EPS -$0.96, revenue $34.22M.

KPTI Earnings FAQ

Answers computed from Karyopharm Therapeutics Inc.'s reported history

KPTI is scheduled to report on Oct 29, 2026, usually before the market opens. Analysts expect EPS of -$0.96.

Over the last 12 quarters with a usable EPS surprise, KPTI beat the consensus estimate 6 times (50%), missed 6 and landed in line 0.

Across its last 10 quarters with a measured reaction, KPTI moved an average of ±9.0% in the first session after reporting. It closed higher 20% of the time; the largest gain was 21.3% and the largest drop -20.0%.

KPTI fell in the first session after 5 of its last 5 EPS beats (100%). A beat that was already priced in, or weaker guidance, can send a stock lower. In 4 of the 5 of those falls where price data is available, the stock had already risen before the report.

Across its last 10 quarters with price data, KPTI moved an average of -1.7% in the 20 trading sessions before reporting and was higher in 40% of them. After a run-up of 3% or more (4 quarters), it fell the next day 100% of the time, averaging -11.4%. After a drop of 3% or more (6 quarters), it rose the next day 33% of the time, averaging +1.3%. This describes past reports; it is not a forecast.

In 7 reports KPTI opened at least 1% away from the previous close. It gave back half or more of that gap by the close 4 of 7 times (57%), and fully reversed 4 times. A fade means the opening move was partly undone during the first session.

How we calculate these numbers · KPTI: 12 reported quarters, latest Aug 13, 2026. Information only, not investment advice.

Earnings this week

Every report this week with expected moves.

Biggest expected earnings moves

Options-implied vs historical move, ranked.