CRISPR Therapeutics AG(CRSP)
NASDAQ

CRSP Stock Analysis — September 2026

$56.49
-0.43 (-0.76%)

CRSP Stock Price Today (September 2026) — CRISPR Therapeutics AG Analysis & Key Metrics 2026-09-03

CRISPR Therapeutics AG (CRSP) is trading at $56.49, down 0.76% today (as of September 2026). The stock continues to show sustained strength above key moving averages, attracting attention from investors looking for Healthcare growth opportunities.

  • According to consensus analyst estimates, the 1-year price target is $75.24 (33.2% upside).
  • Volatility remains elevated (57.01% annualized), implying wide price swings for short-term traders.
  • The fundamental picture, based on the latest financial filings, is nuanced: solid revenue growth (10.41% YoY) alongside significant competitive pressures.

CRSP Stock Analysis: Key Metrics & Valuation (September 2026)

Concise, actionable data for investors

Trend posture
Short-term pullback in long-term uptrend
Analyst 1Y target75.235333.2%
Volatility (30d ann.)57.0114High
RSI (14-day)
51.13 (Neutral)
Debt$783.75M (44.87 D/E)

CRISPR Therapeutics AG - Historical Price & Volume

$56.49
+11.24 (+24.84%)
Price
Volume
Current Price Line
Range: 2Y

Market Cap

$5.51B

Enterprise Value: $4.00B

P/E Ratio

-12.15

Forward P/E: -16.29

Revenue Growth

+10.41%

Year over Year

Analyst Target

$75.24

+33.2% upside potential

Key Investor Questions About CRSP

What investors need to know before buying

Is it a good time to buy CRSP stock?

Based on current market data, CRSP presents a neutral technical setup with caution warranted fundamentals.

  • Technicals say: Neutral (RSI 51.13)
  • Fundamentals say: Caution warranted (high leverage concerns)
Can CRSP sustain revenue growth in the Biotechnology market?

CRSP's growth trajectory depends on its ability to expand within the Biotechnology sector while managing margin pressures.

  • Future growth will depend on performance in core Biotechnology operations.
  • The ability to manage competitive pressures will be crucial for sustained growth.
What are the biggest risks facing CRSP stock?

The primary risks for CRSP investors include debt exposure and competitive dynamics in the Biotechnology industry.

  • $783.75M in debt could be a headwind in a high-rate environment.
  • Fierce competition from established players in Biotechnology.

52-Week Trading Range

52-Week Low$44.12
52-Week High$78.48
Current Price$56.49

Over the past year, CRSP stock traded between $44.12 and $78.48—recovering meaningfully from lows and currently near the higher end. Big swings are likely unless a major catalyst emerges.

Volatility & Risk Profile

30-Day Volatility57.01%
Beta1.46
RSI (14-day)51.13

With 57.01% annualized volatility and β=1.46, the stock exhibits high sensitivity to market moves—making CRSP suitable for investors comfortable with active risk management.

Institutional & Insider Ownership

Insider Ownership5.89%
Institutional Ownership79.42%
Shares Short19.81M

High institutional backing, but elevated short interest signals a potential battleground stock.

Analyst Sentiment & Price Targets

Mean Target
$75.24
Upside Potential
33.2%
Recommendation
buy
Analysts see strong upside potential with a target of $75.24. The 33.2% upside suggests optimistic growth expectations.

Latest News & Headlines

Recent headlines and coverage

ZacksSep 3, 2026

Why Is Ultragenyx (RARE) Up 6.4% Since Last Earnings Report?

Ultragenyx (RARE) reported earnings 30 days ago. What's next for the stock? We take a look at earnings estimates for some clues.

Motley FoolSep 2, 2026

2 Reasons CRISPR Therapeutics Stock Could Soar in the Final 4 Months of 2026

We'll know a little more about the company's prospects by the end of the year.

Simply Wall St.Sep 2, 2026

CRISPR Therapeutics (CRSP) Stock Looks Fully Valued As CTX310 Data Impresses

CRISPR Therapeutics stock has climbed in the shorter term but still carries a heavy five year loss, and current valuation checks point to a company that does not clearly screen as either cheap or expensive. For investors looking at CRISPR Therapeutics today, the share price near US$56.82 sits against a mixed valuation read and a long term track record that remains in the red. The stock has fallen 52.9% over 5 years, which means long term holders are still under water despite more recent...

ZacksSep 2, 2026

Why Is CRISPR Therapeutics (CRSP) Up 7.1% Since Last Earnings Report?

CRISPR Therapeutics (CRSP) reported earnings 30 days ago. What's next for the stock? We take a look at earnings estimates for some clues.

BioPharma DiveSep 2, 2026

Autoimmune CAR-T faces tough questions after Novartis, Bristol Myers study halts

Wall Street analysts believe that a more cautious approach to manufacturing, study enrollment and side effect management could help developers avoid future safety hazards.

Barrons.comSep 1, 2026

Heart-Drug Breakthroughs Can’t Stop Biotech Stocks From Sliding

Impressive results came out on drugs from Amgen, Arrowhead Pharmaceuticals, and Crispr Therapeutics. Their shares are all lower this week.

ZacksAug 26, 2026

Vertex Pharmaceuticals Up 15% in a Month: How to Play the Stock

Vertex's stock is up 15% in a month as strong CF sales, rising non-CF drug revenues and renal pipeline progress boost its growth story.

ZacksAug 24, 2026

4 Gene-Editing Biotech Stocks Worth Watching for Long-Term Gains

CRSP, NTLA, BEAM and EDIT offer distinct gene-editing opportunities, spanning commercial validation, late-stage catalysts and promising early-stage programs.

Motley FoolAug 21, 2026

CRISPR Therapeutics Stock Is Up Only 8% This Year. Is Cathie Wood's Bet on the Gene-Editing Stock Dead Money?

This year, the biotech stock has underperformed both the Nasdaq Biotechnology Index and the S&P 500.

MT NewswiresAug 4, 2026

Crispr Therapeutics Posts "Quiet" Quarter as Casgevy Advances, SiRNA Data Readouts Near, RBC Says

Crispr Therapeutics (CRSP) reported a relatively quiet Q2, with Casgevy continuing to gain commercia

Frequently Asked Questions

Common investor questions about CRISPR Therapeutics AG

CRISPR Therapeutics AG (CRSP) is currently trading at $56.49. The RSI (14-day) is at 51.1, indicating neutral territory. Wall Street analysts have a consensus "buy" recommendation. The mean analyst price target of $75.24 implies 33.2% upside from current levels. Volatility is high at 57.0% annualized, meaning significant price swings are common. Investors should consider their risk tolerance, investment horizon, and portfolio diversification before making a decision.

Based on current valuation metrics for CRISPR Therapeutics AG (CRSP): The trailing P/E ratio is -12.15, which is below the market average of ~20-22, suggesting the stock may be undervalued relative to peers. The forward P/E is -16.29, lower than the trailing P/E, suggesting analysts expect earnings improvement. Price-to-Book is 3.13. Price-to-Sales is 407.87. Valuation should be compared to Biotechnology industry peers for context, as different sectors trade at different multiples.

Based on 17 analysts covering CRSP, the consensus price target is $75.24. This represents a 33.2% upside from the current price of $56.49. The range spans from a low target of $44.00 to a high target of $110.00, reflecting varying levels of optimism among analysts. The consensus recommendation is "buy". Note: Analyst price targets are forward-looking estimates and not guarantees of future performance.

CRISPR Therapeutics AG (CRSP) does not currently pay a regular dividend. The company may be reinvesting profits into growth initiatives, or may not yet be profitable enough to distribute earnings to shareholders.

Key risks for CRISPR Therapeutics AG (CRSP) investors include: 1. High volatility (57.0% annualized)—the stock can experience significant daily price swings. 2. Elevated short interest (23.0% of float) suggests significant bearish sentiment. 3. Broader market and macroeconomic risks (interest rates, inflation, geopolitical events). 4. Biotechnology sector-specific competitive pressures. Investors should diversify and consider their risk tolerance before investing.

Here is CRISPR Therapeutics AG's (CRSP) current debt and financial health profile: Total debt stands at $783.75M. The debt-to-equity ratio is 44.87, which is moderate and generally manageable for most companies. The current ratio is 17.85, indicating strong short-term liquidity. The quick ratio is 17.79. The company holds $2.36B in cash and equivalents. Free cash flow is negative at $-215,845,872, which could limit the company's ability to manage debt obligations.