AstraZeneca PLC(AZN)
NASDAQ

AZN Stock Analysis — September 2026

$164.77
3.14 (1.94%)

AZN Stock Price Today (September 2026) — AstraZeneca PLC Analysis & Key Metrics 2026-09-03

AstraZeneca PLC (AZN) is trading at $164.77, up 1.94% today (as of September 2026). The stock continues to show early recovery signs above the short-term average, attracting attention from investors looking for Healthcare growth opportunities.

  • According to consensus analyst estimates, the 1-year price target is $212.54 (29.0% upside).
  • Volatility remains elevated (18.74% annualized), implying wide price swings for short-term traders.
  • The fundamental picture, based on the latest financial filings, is nuanced: solid revenue growth (6.40% YoY) alongside significant competitive pressures.

AZN Stock Analysis: Key Metrics & Valuation (September 2026)

Concise, actionable data for investors

Trend posture
Short-term pullback in long-term uptrend
Analyst 1Y target212.536429.0%
Volatility (30d ann.)18.7385High
RSI (14-day)
52.69 (Neutral)
Debt$32.35B (64.22 D/E)

AstraZeneca PLC - Historical Price & Volume

$164.77
+3.92 (+2.43%)
Price
Volume
Current Price Line
Range: 2Y

Market Cap

$251.45B

Enterprise Value: $279.80B

P/E Ratio

24.63

Forward P/E: 14.27

Revenue Growth

+6.40%

Year over Year

Analyst Target

$212.54

+29.0% upside potential

Key Investor Questions About AZN

What investors need to know before buying

Is it a good time to buy AZN stock?

Based on current market data, AZN presents a neutral technical setup with caution warranted fundamentals.

  • Technicals say: Neutral (RSI 52.69)
  • Fundamentals say: Caution warranted (high leverage concerns)
Can AZN sustain revenue growth in the Drug Manufacturers - General market?

AZN's growth trajectory depends on its ability to expand within the Drug Manufacturers - General sector while managing margin pressures.

  • Future growth will depend on performance in core Drug Manufacturers - General operations.
  • The ability to manage competitive pressures will be crucial for sustained growth.
What are the biggest risks facing AZN stock?

The primary risks for AZN investors include debt exposure and competitive dynamics in the Drug Manufacturers - General industry.

  • $32.35B in debt could be a headwind in a high-rate environment.
  • Fierce competition from established players in Drug Manufacturers - General.

52-Week Trading Range

52-Week Low$145.80
52-Week High$212.71
Current Price$164.77

Over the past year, AZN stock traded between $145.80 and $212.71—recovering meaningfully from lows and currently near the higher end. Big swings are likely unless a major catalyst emerges.

Volatility & Risk Profile

30-Day Volatility18.74%
Beta0.37
RSI (14-day)52.69

With 18.74% annualized volatility and β=0.37, the stock exhibits low sensitivity to market moves—making AZN suitable for investors comfortable with active risk management.

Institutional & Insider Ownership

Insider Ownership4.70%
Institutional Ownership64.82%
Shares Short1.89M

High institutional backing, but elevated short interest signals a potential battleground stock.

Analyst Sentiment & Price Targets

Mean Target
$212.54
Upside Potential
29.0%
Recommendation
strong_buy
Analysts see strong upside potential with a target of $212.54. The 29.0% upside suggests optimistic growth expectations.

Latest News & Headlines

Recent headlines and coverage

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Simply Wall St.Sep 2, 2026

TEZSPIRE’s Positive EoE Phase 3 Results Could Be A Game Changer For Amgen (AMGN)

Amgen and AstraZeneca recently reported positive Phase 3 CROSSING results showing TEZSPIRE improved histologic remission and dysphagia symptoms in patients with eosinophilic esophagitis, with effects sustained through week 52 and a safety profile broadly consistent with prior use. Because EoE remains poorly controlled for nearly half of patients on existing therapies, TEZSPIRE’s epithelial-targeting mechanism could meaningfully expand its role beyond severe asthma and nasal polyps if...

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Top Stock Reports for AMD, Costco & AstraZeneca

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Krystal Biotech (KRYS) reported earnings 30 days ago. What's next for the stock? We take a look at earnings estimates for some clues.

ZacksSep 2, 2026

AZN Stock Down 20% in 6 Months: How to Play After Pipeline Setbacks

AstraZeneca's pipeline setbacks weigh on the stock, but blockbuster drugs, oncology growth and a strong launch pipeline offer reasons to stay invested.

ZacksSep 2, 2026

AZN's Tagrisso Plus Orpathys Study in First-Line NSCLC Meets Goal

AstraZeneca reports positive SANOVO data, showing Tagrisso plus Orpathys improved PFS in first-line EGFR-mutated NSCLC.

Simply Wall St.Sep 2, 2026

AstraZeneca (LSE:AZN) Stock Trades At a Discount Following Its 57% Run

AstraZeneca stock has delivered a 56.7% total return over the past 5 years, yet the broader valuation checks still suggest the shares lean cheap. Recent share price weakness over shorter periods sits against a high overall value score and a market view that the stock trades on the low side of its usual multiples. A 56.7% gain over 5 years highlights that AstraZeneca has already rewarded patient investors, which makes the current discount signal from valuation checks more striking. Fresh...

GuruFocus.comSep 1, 2026

AstraZeneca's $80 Billion Plan Gets Another Tagrisso Win

The SANOVO trial showed Tagrisso plus Orpathys significantly delayed progression in previously untreated advanced lung cancer.

Simply Wall St.Sep 1, 2026

What Does AstraZeneca (LSE:AZN) Gain From Its Latest Oncology Advances?

AstraZeneca (LSE:AZN) received European Union approval for a first-line Enhertu plus pertuzumab combination for HER2-positive breast cancer, marking the first new first-line regimen in over a decade. The company completed a major global license agreement for lung cancer drug ZEGFROVY, securing worldwide rights to a next-generation EGFR inhibitor with breakthrough designations. Together, these oncology milestones expand AstraZeneca’s approved treatment options in breast cancer and reinforce...

Frequently Asked Questions

Common investor questions about AstraZeneca PLC

AstraZeneca PLC (AZN) is currently trading at $164.77. The RSI (14-day) is at 52.7, indicating neutral territory. Wall Street analysts have a consensus "strong_buy" recommendation. The mean analyst price target of $212.54 implies 29.0% upside from current levels. Volatility is low at 18.7% annualized, meaning price movements are relatively contained. Investors should consider their risk tolerance, investment horizon, and portfolio diversification before making a decision.

Based on current valuation metrics for AstraZeneca PLC (AZN): The trailing P/E ratio is 24.63, which is in line with broader market averages. The forward P/E is 14.27, lower than the trailing P/E, suggesting analysts expect earnings improvement. The PEG ratio is 1.42, near 1.0, suggesting roughly fair value relative to growth. Price-to-Book is 5.08. Price-to-Sales is 4.16. Valuation should be compared to Drug Manufacturers - General industry peers for context, as different sectors trade at different multiples.

Based on 11 analysts covering AZN, the consensus price target is $212.54. This represents a 29.0% upside from the current price of $164.77. The range spans from a low target of $184.00 to a high target of $240.00, reflecting varying levels of optimism among analysts. The consensus recommendation is "strong_buy". Note: Analyst price targets are forward-looking estimates and not guarantees of future performance.

Yes, AstraZeneca PLC (AZN) pays a dividend with a current yield of approximately 1.94%. The annualized dividend rate is $3.23 per share. The payout ratio is 47.4%, which is conservative and suggests the dividend is well-covered by earnings with room for future increases. The most recent ex-dividend date was 2026-08-07T00:00:00.000Z.

Key risks for AstraZeneca PLC (AZN) investors include: 1. Elevated short interest (12.0% of float) suggests significant bearish sentiment. 2. Broader market and macroeconomic risks (interest rates, inflation, geopolitical events). 3. Drug Manufacturers - General sector-specific competitive pressures. Investors should diversify and consider their risk tolerance before investing.

Here is AstraZeneca PLC's (AZN) current debt and financial health profile: Total debt stands at $32.35B. The debt-to-equity ratio is 64.22, which is moderate and generally manageable for most companies. The current ratio is 0.89, which is below 1.0 and may indicate short-term liquidity concerns. The quick ratio is 0.66. The company holds $4.97B in cash and equivalents. Free cash flow is positive at $4.91B, providing a cushion for debt servicing and shareholder returns.