Arrowhead Pharmaceuticals, Inc.(ARWR)
NASDAQ

ARWR Stock Analysis — September 2026

$86.49
1.12 (1.31%)

ARWR Stock Price Today (September 2026) — Arrowhead Pharmaceuticals, Inc. Analysis & Key Metrics 2026-09-03

Arrowhead Pharmaceuticals, Inc. (ARWR) is trading at $86.49, up 1.31% today (as of September 2026). The stock continues to show sustained strength above key moving averages, attracting attention from investors looking for Healthcare growth opportunities.

  • According to consensus analyst estimates, the 1-year price target is $110.18 (27.4% upside).
  • Volatility remains elevated (28.11% annualized), implying wide price swings for short-term traders.
  • The fundamental picture, based on the latest financial filings, is nuanced: solid revenue growth (1.71% YoY) alongside significant competitive pressures.

ARWR Stock Analysis: Key Metrics & Valuation (September 2026)

Concise, actionable data for investors

Trend posture
Short-term pullback in long-term uptrend
Analyst 1Y target110.181827.4%
Volatility (30d ann.)28.1127High
RSI (14-day)
51.81 (Neutral)
Debt$1.38B (295.98 D/E)

Arrowhead Pharmaceuticals, Inc. - Historical Price & Volume

$86.49
+63.24 (+272.00%)
Price
Volume
Current Price Line
Range: 2Y

Market Cap

$11.64B

Enterprise Value: $11.78B

P/E Ratio

-38.96

Forward P/E: -17.05

Revenue Growth

+1.71%

Year over Year

Analyst Target

$110.18

+27.4% upside potential

Key Investor Questions About ARWR

What investors need to know before buying

Is it a good time to buy ARWR stock?

Based on current market data, ARWR presents a neutral technical setup with caution warranted fundamentals.

  • Technicals say: Neutral (RSI 51.81)
  • Fundamentals say: Caution warranted (high leverage concerns)
Can ARWR sustain revenue growth in the Biotechnology market?

ARWR's growth trajectory depends on its ability to expand within the Biotechnology sector while managing margin pressures.

  • Future growth will depend on performance in core Biotechnology operations.
  • The ability to manage competitive pressures will be crucial for sustained growth.
What are the biggest risks facing ARWR stock?

The primary risks for ARWR investors include debt exposure and competitive dynamics in the Biotechnology industry.

  • $1.38B in debt could be a headwind in a high-rate environment.
  • Fierce competition from established players in Biotechnology.

52-Week Trading Range

52-Week Low$22.73
52-Week High$95.49
Current Price$86.49

Over the past year, ARWR stock traded between $22.73 and $95.49—recovering meaningfully from lows and currently near the higher end. Big swings are likely unless a major catalyst emerges.

Volatility & Risk Profile

30-Day Volatility28.11%
Beta1.67
RSI (14-day)51.81

With 28.11% annualized volatility and β=1.67, the stock exhibits high sensitivity to market moves—making ARWR suitable for investors comfortable with active risk management.

Institutional & Insider Ownership

Insider Ownership3.66%
Institutional Ownership85.60%
Shares Short9.21M

High institutional backing, but elevated short interest signals a potential battleground stock.

Analyst Sentiment & Price Targets

Mean Target
$110.18
Upside Potential
27.4%
Recommendation
strong_buy
Analysts see strong upside potential with a target of $110.18. The 27.4% upside suggests optimistic growth expectations.

Latest News & Headlines

Recent headlines and coverage

Simply Wall St.Sep 1, 2026

Is Arrowhead Pharmaceuticals (ARWR) Undervalued As SHASTA 3 And SHASTA 4 Data Impress?

Arrowhead Pharmaceuticals (ARWR) attracted fresh attention after presenting pivotal Phase 3 SHASTA-3 and SHASTA-4 data for plozasiran at the ESC Congress 2026. The company highlighted triglyceride reductions and fewer acute pancreatitis events in severe hypertriglyceridemia. Arrowhead Pharmaceuticals has seen its share price give back some ground in the past week, with the 1-day share price return down 2.97% and the 7-day share price return down 5%. At the same time, the 90-day share price...

MarketBeatAug 31, 2026

Arrowhead’s Plozasiran Cuts Triglycerides, Pancreatitis Risk in Phase 3 Trials

Arrowhead Pharmaceuticals (NASDAQ:ARWR) presented 12-month results from its Phase 3 SHASTA-3 and SHASTA-4 trials evaluating plozasiran in adults with severe hypertriglyceridemia, reporting substantial reductions in triglycerides and acute pancreatitis events versus placebo. The company said the data

Insider MonkeyAug 28, 2026

Could Arrowhead Pharmaceuticals (ARWR)’s Plozasiran Become the Catalyst for a Major Stock Re-rating?

Arrowhead Pharmaceuticals, Inc. (NASDAQ:ARWR) reached a major European milestone on August 17 when it announced the availability of REDEMPLO for adults with Familial Chylomicronemia Syndrome (FCS) in Germany. Following European Commission authorization in June 2026, the drug is now listed in the Lauer-Taxe database for prescribing and reimbursement. Unlike existing options requiring genetic confirmation, REDEMPLO […]

BioPharma DiveAug 7, 2026

‘Significant’ demand for Revolution drug; Intellia pinpoints liver toxicity culprit

Early indicators from a compassionate use plan led analysts to hike projections for daraxonrasib. Elsewhere, Intellia believes it’s answered a key safety question and Arrowhead moved to catch a rival.

GuruFocus.comAug 5, 2026

Arrowhead Pharmaceuticals Inc (ARWR) (Q3 2026) Earnings Call Highlights: Strong Phase III Data ...

Arrowhead Pharmaceuticals Inc (ARWR) reports robust clinical progress and commercial growth, despite a wider net loss in Q3 2026.

MarketBeatAug 4, 2026

Arrowhead Pharmaceuticals Q3 Earnings Call Highlights

Arrowhead Pharmaceuticals (NASDAQ:ARWR) reported positive Phase III results for plozasiran in severe hypertriglyceridemia (SHTG), accelerating plans for a supplemental New Drug Application and highlighting continued growth in the launch of its REDEMPLO therapy for familial chylomicronemia syndrome (

Simply Wall St.Jul 30, 2026

The Bull Case For Arrowhead Pharmaceuticals (ARWR) Could Change Following Dual Phase 3 RNAi Cardiometabolic Milestones

Arrowhead Pharmaceuticals recently reported that its siRNA drug plozasiran met all primary and key secondary endpoints in two global Phase 3 trials for severe hypertriglyceridemia, while also completing patient enrollment for the YOSEMITE Phase 3 trial of zodasiran in the ultra-rare condition homozygous familial hypercholesterolemia. Together, these late-stage milestones highlight Arrowhead’s push to expand its RNAi portfolio into high-need cardiometabolic diseases, potentially broadening...

Investor's Business DailyJul 23, 2026

The 'Best-Case Scenario' That Shot Arrowhead Stock Sky-High

Arrowhead Pharmaceuticals' triglycerides-buster hit the "best-case scenario" in two studies Wednesday, leading the stock to skyrocket.

TrefisJul 23, 2026

Is Arrowhead Pharmaceuticals Stock A Smart Buy After Its Transition To A Commercial Company?

With its first drug on the market and a pipeline full of catalysts, the company asks investors to weigh a powerful growth story against an elevated valuation and a history of volatility.

StocktwitsJul 22, 2026

ARWR Stock Clocks Best Day In Nearly 8 Months As Analyst Lifts Price Target On Plozasiran Data

Chardan analyst Keay Nakae raised the firm's price target on Arrowhead to $115 from $90 and keeps a Buy rating on the shares.

Frequently Asked Questions

Common investor questions about Arrowhead Pharmaceuticals, Inc.

Arrowhead Pharmaceuticals, Inc. (ARWR) is currently trading at $86.49. The RSI (14-day) is at 51.8, indicating neutral territory. Wall Street analysts have a consensus "strong_buy" recommendation. The mean analyst price target of $110.18 implies 27.4% upside from current levels. Volatility is moderate at 28.1% annualized, meaning price movements are relatively contained. Investors should consider their risk tolerance, investment horizon, and portfolio diversification before making a decision.

Based on current valuation metrics for Arrowhead Pharmaceuticals, Inc. (ARWR): The trailing P/E ratio is -38.96, which is below the market average of ~20-22, suggesting the stock may be undervalued relative to peers. The forward P/E is -17.05. Price-to-Book is 26.23. Price-to-Sales is 18.25. Valuation should be compared to Biotechnology industry peers for context, as different sectors trade at different multiples.

Based on 11 analysts covering ARWR, the consensus price target is $110.18. This represents a 27.4% upside from the current price of $86.49. The range spans from a low target of $100.00 to a high target of $126.00, reflecting varying levels of optimism among analysts. The consensus recommendation is "strong_buy". Note: Analyst price targets are forward-looking estimates and not guarantees of future performance.

Arrowhead Pharmaceuticals, Inc. (ARWR) does not currently pay a regular dividend. The company may be reinvesting profits into growth initiatives, or may not yet be profitable enough to distribute earnings to shareholders.

Key risks for Arrowhead Pharmaceuticals, Inc. (ARWR) investors include: 1. Moderate volatility (28.1% annualized)—price swings are notable. 2. Elevated debt levels (D/E ratio of 295.98) which could pressure margins in a rising rate environment. 3. Broader market and macroeconomic risks (interest rates, inflation, geopolitical events). 4. Biotechnology sector-specific competitive pressures. Investors should diversify and consider their risk tolerance before investing.

Here is Arrowhead Pharmaceuticals, Inc.'s (ARWR) current debt and financial health profile: Total debt stands at $1.38B. The debt-to-equity ratio is 295.98, which is high and could pose financial risk if earnings decline or borrowing costs increase. The current ratio is 5.90, indicating strong short-term liquidity. The quick ratio is 5.71. The company holds $1.60B in cash and equivalents. Free cash flow is negative at $-48,628,124, which could limit the company's ability to manage debt obligations.