Arrowhead Pharmaceuticals, Inc.(ARWR)
NASDAQ

ARWR Stock Analysis — April 2026

$65.35
2.43 (3.86%)

ARWR Stock Price Today (April 2026) — Arrowhead Pharmaceuticals, Inc. Analysis & Key Metrics 2026-04-02

Arrowhead Pharmaceuticals, Inc. (ARWR) is trading at $65.35, up 3.86% today (as of April 2026). The stock continues to show sustained strength above key moving averages, attracting attention from investors looking for Healthcare growth opportunities.

  • According to consensus analyst estimates, the 1-year price target is $81.09 (24.1% upside).
  • Volatility remains elevated (49.00% annualized), implying wide price swings for short-term traders.
  • The fundamental picture, based on the latest financial filings, is nuanced: solid revenue growth (104.61% YoY) alongside significant competitive pressures.

ARWR Stock Analysis: Key Metrics & Valuation (April 2026)

Concise, actionable data for investors

Trend posture
Short-term pullback in long-term uptrend
Analyst 1Y target81.0924.1%
Volatility (30d ann.)49.001High
RSI (14-day)
55.75 (Neutral)
Debt$698.16M (124.07 D/E)

Arrowhead Pharmaceuticals, Inc. - Historical Price & Volume

$65.35
+39.67 (+154.48%)
Price
Volume
Current Price Line
Range: 2Y

Market Cap

$8.55B

Enterprise Value: $8.32B

P/E Ratio

38.14

Forward P/E: -14.20

Revenue Growth

+104.61%

Year over Year

Analyst Target

$81.09

+24.1% upside potential

Key Investor Questions About ARWR

What investors need to know before buying

Is it a good time to buy ARWR stock?

Based on current market data, ARWR presents a neutral technical setup with caution warranted fundamentals.

  • Technicals say: Neutral (RSI 55.75)
  • Fundamentals say: Caution warranted (high leverage concerns)
Can ARWR sustain revenue growth in the Biotechnology market?

ARWR's growth trajectory depends on its ability to expand within the Biotechnology sector while managing margin pressures.

  • Future growth will depend on performance in core Biotechnology operations.
  • The ability to manage competitive pressures will be crucial for sustained growth.
What are the biggest risks facing ARWR stock?

The primary risks for ARWR investors include debt exposure and competitive dynamics in the Biotechnology industry.

  • $698.16M in debt could be a headwind in a high-rate environment.
  • Fierce competition from established players in Biotechnology.

52-Week Trading Range

52-Week Low$9.57
52-Week High$76.76
Current Price$65.35

Over the past year, ARWR stock traded between $9.57 and $76.76—recovering meaningfully from lows and currently near the higher end. Big swings are likely unless a major catalyst emerges.

Volatility & Risk Profile

30-Day Volatility49.00%
Beta1.30
RSI (14-day)55.75

With 49.00% annualized volatility and β=1.30, the stock exhibits high sensitivity to market moves—making ARWR suitable for investors comfortable with active risk management.

Institutional & Insider Ownership

Insider Ownership3.80%
Institutional Ownership84.41%
Shares Short11.43M

High institutional backing, but elevated short interest signals a potential battleground stock.

Analyst Sentiment & Price Targets

Mean Target
$81.09
Upside Potential
24.1%
Recommendation
buy
Analysts see strong upside potential with a target of $81.09. The 24.1% upside suggests optimistic growth expectations.

Latest News & Headlines

Recent headlines and coverage

Simply Wall St.Mar 29, 2026

Arrowhead Plozasiran Data Supports Triglyceride Reduction And Valuation Upside Potential

Arrowhead Pharmaceuticals released two year extension data for its RNAi therapy plozasiran in patients with severe and moderate hypertriglyceridemia. The study showed sustained triglyceride reduction alongside a favorable safety profile over the long term. Results were presented at a major cardiology conference and focus on patient groups at high risk of acute pancreatitis with limited treatment options. For investors tracking NasdaqGS:ARWR, the plozasiran update arrives after a mixed share...

ZacksMar 26, 2026

SRPT Stock Surges on Promising Early Results From siRNA Programs

Sarepta Therapeutics shares surge 35% as early data from two siRNA therapies show strong target knockdown, safety and muscle delivery potential.

Barrons.comMar 25, 2026

Johnson & Johnson Exits 3 Biotechs but Keeps Stakes in These Rumored Acquisition Targets

Johnson & Johnson’s restated fourth-quarter holdings report, filed last week, reveals that the company exited three biotechs while retaining its stakes in several rumored acquisition targets. The changes included the sale of 247,598 shares in Arrowhead Pharmaceuticals previously a partner of Johnson & Johnson’s Janssen unit, which rebranded as its Innovative Medicine division. Johnson & Johnson also exited BiomX another former collaborator, through the sale of 96,866 shares.

24/7 Wall St.Mar 25, 2026

Sarepta Therapeutics Zooms 20% Higher on Promising Clinical Data: Is SRPT Ready for a Bigger Breakout?

Sarepta Therapeutics (NASDAQ:SRPT) stock is up approximately 20% in early trading on Wednesday after the company released its first-ever clinical data from two siRNA programs targeting rare neuromuscular diseases with no currently approved treatments. SRPT stock, which closed at $17.61 on Tuesday, is attracting fresh investor attention after years of turbulence tied to its gene ... Sarepta Therapeutics Zooms 20% Higher on Promising Clinical Data: Is SRPT Ready for a Bigger Breakout?

BioPharma DiveMar 25, 2026

Sarepta sees early success with RNAi drugs from Arrowhead

Long-awaited results from Phase 1/2 studies lifted Sarepta’s stock and, according to the company, suggest potential for two medicines to treat muscle-weakening conditions.

ZacksMar 20, 2026

Sarepta Plans FDA Filings Seeking Full Approval for Two DMD Therapies

SRPT plans FDA filings to convert Amondys 45 and Vyondys 53 to full approvals, leveraging new data despite a missed endpoint in its confirmatory study.

Simply Wall St.Mar 20, 2026

A Look At Arrowhead Pharmaceuticals (ARWR) Valuation As Recent Momentum Cools After A Strong Run

With no single headline event driving Arrowhead Pharmaceuticals (ARWR) today, recent trading and fundamentals still give you a few concrete markers to watch as you think about the stock. See our latest analysis for Arrowhead Pharmaceuticals. At a share price of US$56.96, Arrowhead’s 1-day and 7-day share price returns of 0.44% and 3.54% sit against a 30-day and 90-day share price pullback, while the 1-year total shareholder return is very large and well above the 3-year total shareholder...

Insider MonkeyMar 17, 2026

Arrowhead Pharmaceuticals Inc. (ARWR): Billionaire Ken Fisher Bets Big on Pharma

Arrowhead Pharmaceuticals, Inc. (NASDAQ:ARWR) is one of Billionaire Ken Fisher’s 15 Most Notable Moves for 2026. Arrowhead Pharmaceuticals, Inc. (NASDAQ:ARWR) is a relatively recent addition to the 13F portfolio of Fisher Asset Management. The fund first disclosed a stake in the firm in filings for the second quarter of 2024, comprising close to 12,000 shares […]

ZacksMar 17, 2026

SRPT Stock Up as Enrollment Begins in DMD Gene Therapy Safety Study

Sarepta gains as enrollment begins in a new ENDEAVOR study cohort testing a sirolimus regimen to improve Elevidys safety in DMD patients.

Insider MonkeyMar 14, 2026

Arrowhead (ARWR) FQ1 2026 Revenue Hits $264M as REDEMPLO Approval Marks Commercial Shift

Arrowhead Pharmaceuticals Inc. (NASDAQ:ARWR) is one of the best multibagger stocks to invest in according to billionaires. On February 5, Arrowhead Pharmaceuticals achieved a strategic turning point in FQ1 2026, transitioning into a commercial-stage organization following the US FDA approval of its first medicine, REDEMPLO (plozasiran). This siRNA therapeutic, designed to treat familial chylomicronemia syndrome/FCS, […]

Frequently Asked Questions

Common investor questions about Arrowhead Pharmaceuticals, Inc.

Arrowhead Pharmaceuticals, Inc. (ARWR) is currently trading at $65.35. The RSI (14-day) is at 55.7, indicating neutral territory. Wall Street analysts have a consensus "buy" recommendation. The mean analyst price target of $81.09 implies 24.1% upside from current levels. Volatility is high at 49.0% annualized, meaning significant price swings are common. Investors should consider their risk tolerance, investment horizon, and portfolio diversification before making a decision.

Based on current valuation metrics for Arrowhead Pharmaceuticals, Inc. (ARWR): The trailing P/E ratio is 38.14, which is above the market average, indicating investors are pricing in higher growth expectations. The forward P/E is -14.20, lower than the trailing P/E, suggesting analysts expect earnings improvement. Price-to-Book is 14.75. Price-to-Sales is 7.83. Valuation should be compared to Biotechnology industry peers for context, as different sectors trade at different multiples.

Based on 11 analysts covering ARWR, the consensus price target is $81.09. This represents a 24.1% upside from the current price of $65.35. The range spans from a low target of $35.00 to a high target of $110.00, reflecting varying levels of optimism among analysts. The consensus recommendation is "buy". Note: Analyst price targets are forward-looking estimates and not guarantees of future performance.

Arrowhead Pharmaceuticals, Inc. (ARWR) does not currently pay a regular dividend. The company may be reinvesting profits into growth initiatives, or may not yet be profitable enough to distribute earnings to shareholders.

Key risks for Arrowhead Pharmaceuticals, Inc. (ARWR) investors include: 1. High volatility (49.0% annualized)—the stock can experience significant daily price swings. 2. Elevated debt levels (D/E ratio of 124.07) which could pressure margins in a rising rate environment. 3. Elevated short interest (11.4% of float) suggests significant bearish sentiment. 4. Broader market and macroeconomic risks (interest rates, inflation, geopolitical events). 5. Biotechnology sector-specific competitive pressures. Investors should diversify and consider their risk tolerance before investing.

Here is Arrowhead Pharmaceuticals, Inc.'s (ARWR) current debt and financial health profile: Total debt stands at $698.16M. The debt-to-equity ratio is 124.07, which is elevated and warrants monitoring, especially in a rising interest rate environment. The current ratio is 3.38, indicating strong short-term liquidity. The quick ratio is 3.26. The company holds $914.71M in cash and equivalents. Free cash flow is positive at $170.73M, providing a cushion for debt servicing and shareholder returns.