Pfizer Inc.(PFE)
NASDAQ

PFE Stock Analysis — September 2026

$28.45
-0.36 (-1.25%)

PFE Stock Price Today (September 2026) — Pfizer Inc. Analysis & Key Metrics 2026-09-04

Pfizer Inc. (PFE) is trading at $28.45, down 1.25% today (as of September 2026). The stock continues to show sustained strength above key moving averages, attracting attention from investors looking for Healthcare growth opportunities.

  • According to consensus analyst estimates, the 1-year price target is $28.61 (0.5% upside).
  • Volatility remains elevated (20.33% annualized), implying wide price swings for short-term traders.
  • The fundamental picture, based on the latest financial filings, is nuanced: solid revenue growth (2.60% YoY) alongside significant competitive pressures.

PFE Stock Analysis: Key Metrics & Valuation (September 2026)

Concise, actionable data for investors

Trend posture
Short-term pullback in long-term uptrend
Analyst 1Y target28.60580.5%
Volatility (30d ann.)20.3288High
RSI (14-day)
62.32 (Neutral)
Debt$63.48B (74.25 D/E)

Pfizer Inc. - Historical Price & Volume

$28.45
+2.32 (+8.88%)
Price
Volume
Current Price Line
Range: 2Y

Market Cap

$162.21B

Enterprise Value: $211.44B

P/E Ratio

36.95

Forward P/E: 9.83

Revenue Growth

+2.60%

Year over Year

Analyst Target

$28.61

+0.5% upside potential

Key Investor Questions About PFE

What investors need to know before buying

Is it a good time to buy PFE stock?

Based on current market data, PFE presents a neutral technical setup with caution warranted fundamentals.

  • Technicals say: Neutral (RSI 62.32)
  • Fundamentals say: Caution warranted (high leverage concerns)
Can PFE sustain revenue growth in the Drug Manufacturers - General market?

PFE's growth trajectory depends on its ability to expand within the Drug Manufacturers - General sector while managing margin pressures.

  • Future growth will depend on performance in core Drug Manufacturers - General operations.
  • The ability to manage competitive pressures will be crucial for sustained growth.
What are the biggest risks facing PFE stock?

The primary risks for PFE investors include debt exposure and competitive dynamics in the Drug Manufacturers - General industry.

  • $63.48B in debt could be a headwind in a high-rate environment.
  • Fierce competition from established players in Drug Manufacturers - General.

52-Week Trading Range

52-Week Low$23.58
52-Week High$28.75
Current Price$28.45

Over the past year, PFE stock traded between $23.58 and $28.75—recovering meaningfully from lows and currently near the higher end. Big swings are likely unless a major catalyst emerges.

Volatility & Risk Profile

30-Day Volatility20.33%
Beta0.46
RSI (14-day)62.32

With 20.33% annualized volatility and β=0.46, the stock exhibits low sensitivity to market moves—making PFE suitable for investors comfortable with active risk management.

Institutional & Insider Ownership

Insider Ownership10.10%
Institutional Ownership69.15%
Shares Short149.27M

High institutional backing, but elevated short interest signals a potential battleground stock.

Analyst Sentiment & Price Targets

Mean Target
$28.61
Upside Potential
0.5%
Recommendation
buy
Analyst target of $28.61 suggests modest upside with 0.5% potential gain.

Latest News & Headlines

Recent headlines and coverage

24/7 Wall St.Sep 7, 2026

Forget the Dividend. This Could Be the Real Reason to Buy Pfizer Stock Now

Pfizer's 5.91% yield draws most of the headlines, but a quietly rerated stock and a pipeline loaded with 2026 catalysts are building a separate case altogether for investors willing to look past the dividend.

Motley FoolSep 7, 2026

This Is What I'd Do With Pfizer Stock Right Now

The pharmaceutical stock is struggling, but its dividend can be highly valuable to income investors.

ZacksSep 7, 2026

Here's How Trump's Drug Deals Are Likely to Impact Healthcare ETFs

Trump's latest MFN drug-pricing deals create a mixed outlook for the broader healthcare sector ETFs.

ZacksSep 7, 2026

AstraZeneca Secures FDA Nod for New Breast Cancer Therapy Etcamah

AZN's Etcamah wins accelerated FDA approval for certain advanced breast cancer patients, backed by a 56% risk reduction in progression or death.

Motley FoolSep 4, 2026

AbbVie vs. Pfizer: Which Healthcare Stock Is a Better Buy in 2026?

AbbVie's immunology pivot is offsetting Humira's decline, while Pfizer trades at half the valuation despite patent risks ahead.

TrefisSep 4, 2026

Was JNJ Stock Rally Actually Its Own?

Johnson & Johnson (JNJ) stock returned 59.9% over the past year, against 21.1% for the S&P 500. The company has a clean story for it. The biosimilar hit it had been bracing for arrived and was absorbed, and its talc litigation now has a proposed ending. Both are real. The first does not explain a move that size, and the second is not finished.

24/7 Wall St.Sep 4, 2026

Pfizer’s Stock Has Been Crushed—Is Its 6% Dividend Finally Worth Buying?

Pfizer shareholders are collecting a 6% yield while the stock bleeds value, and the CEO just made a bold promise about keeping that payout alive through what could be the company's toughest stretch in years.

ZacksSep 4, 2026

AMGN's MariTide: Can Convenience Drive its Obesity Market Share?

Amgen's MariTide could target obesity with less frequent dosing, offering a convenience edge as competition from Lilly and Novo Nordisk intensifies.

BioPharma DiveSep 4, 2026

Trailing rivals, AbbVie scores win with dual-acting myeloma drug

The drugmaker is leaning on a better side effect profile compared to drugs from J&J, Pfizer and Regeneron as it pushes etentamig toward FDA submission.

BioPharma DiveSep 4, 2026

Ionis’ rare neurology drug approved; Pfizer inks an ADC deal

Zanvastro is now the first approved medicine for Alexander disease. Elsewhere, an immune system specialist posted positive results and a cell therapy developer turned to layoffs.

Frequently Asked Questions

Common investor questions about Pfizer Inc.

Pfizer Inc. (PFE) is currently trading at $28.45. The RSI (14-day) is at 62.3, indicating neutral territory. Wall Street analysts have a consensus "buy" recommendation. The mean analyst price target of $28.61 implies 0.5% upside from current levels. Volatility is moderate at 20.3% annualized, meaning price movements are relatively contained. Investors should consider their risk tolerance, investment horizon, and portfolio diversification before making a decision.

Based on current valuation metrics for Pfizer Inc. (PFE): The trailing P/E ratio is 36.95, which is above the market average, indicating investors are pricing in higher growth expectations. The forward P/E is 9.83, lower than the trailing P/E, suggesting analysts expect earnings improvement. The PEG ratio is 2.71, above 2.0, suggesting the stock may be overvalued relative to its expected growth. Price-to-Book is 1.90. Price-to-Sales is 2.55. Valuation should be compared to Drug Manufacturers - General industry peers for context, as different sectors trade at different multiples.

Based on 26 analysts covering PFE, the consensus price target is $28.61. This represents a 0.5% upside from the current price of $28.45. The range spans from a low target of $25.00 to a high target of $35.75, reflecting varying levels of optimism among analysts. The consensus recommendation is "buy". Note: Analyst price targets are forward-looking estimates and not guarantees of future performance.

Yes, Pfizer Inc. (PFE) pays a dividend with a current yield of approximately 6.05%. The annualized dividend rate is $1.72 per share. The payout ratio is 226.3%, which exceeds 100%—this means the company is paying out more than it earns, which may not be sustainable long-term. The most recent ex-dividend date was 2026-07-24T00:00:00.000Z.

Key risks for Pfizer Inc. (PFE) investors include: 1. Unsustainable dividend payout ratio (226%) could lead to a dividend cut. 2. Broader market and macroeconomic risks (interest rates, inflation, geopolitical events). 3. Drug Manufacturers - General sector-specific competitive pressures. Investors should diversify and consider their risk tolerance before investing.

Here is Pfizer Inc.'s (PFE) current debt and financial health profile: Total debt stands at $63.48B. The debt-to-equity ratio is 74.25, which is moderate and generally manageable for most companies. The current ratio is 1.27, indicating adequate short-term liquidity. The quick ratio is 0.85. The company holds $11.70B in cash and equivalents. Free cash flow is positive at $12.49B, providing a cushion for debt servicing and shareholder returns.